Fig. 5.
Impairments of remote memory stabilization following contextual fear conditioning in 5XFAD mice at <4 months of age. 5XFAD mice and their wild-type littermate mice were trained with one CS-US pairing for contextual fear conditioning. 5XFAD mice show significantly lower levels of contextual freezing than wild-type mice when tested 30 days after training (n = 8–15 mice per group). * P<0.05 versus wild-type controls. All data are presented as mean ± SEM.