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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Cancer Res. 2009 May 19;69(11):4589–4597. doi: 10.1158/0008-5472.CAN-08-4117

Figure 3. Pin1 and Pin1(S16A) promote relocalization of v-Rel and hc-Rel to the nucleus in the absence of stimuli.

Figure 3

(A) Immunofluorescence showing that co-expression of Pin1 or Pin1(S16A) provokes nuclear translocation of v-Rel in CEFs infected with bicistronic retroviral vectors, in contrast to Pin1(S16E). (B) Pin1 or Pin1(S16A) similarly induce accumulation of hc-Rel in the nucleus of infected CEFs. (C) Immunofluorescence showing relocalization of hc-Rel to the nucleus of transformed CSCs coexpressing hc-Rel proteins with Pin1, but not in those co-expressing Pin1(S16E).