Table 2.
BAL Fluid Cell Characteristics
| IPF (n = 19) | Sar (n = 6) | CVD-IP (n = 8) | HV (n = 6) | |
| Total cells (105/ml) |
6.2 ± 0.8 (1.9-14.8) |
4.9 ± 0.3 (4.0-6.0) |
11.2 ± 3.1*#£ (1.1-27.9) |
2.7 ± 0.5 (0.6-4.0) |
| Macrophage (%) |
78.0 ± 2.6∫ (60.2-97.0) |
62.9 ± 10.8* (29.5-95.0) | 44.0 ± 9.9"§ (5.5-74.5) | 95.6 ± 0.3§$ (94.7-96.6) |
| Lymphocyte (%) |
11.3 ± 2.1 (0-27.4) |
34.6 ± 10.5*‡ (5.0-68.5) |
33.8 ± 8.7*‡ (12.0-87.5) |
3.1 ± 0.2 (2.6-4.0) |
| Neutrophil (%) |
6.1 ± 1.4 (1.0-23.0) |
1.7 ± 0.8 (0-4.0) |
18.4 ± 8.6|#£ (0-65.5) |
1.1 ± 0.1 (0.7-1.6) |
| Eosinophil (%) |
4.4 ± 1.1∫# (0-14.5) |
0.5 ± 0.3 (0-1.9) |
1.7 ± 0.9 (0-7.5) |
0.2 ± 0.2 (0-0.9) |
| CD4/CD8 | 3.1 ± 0.6 (0.2-9.6) |
11.2 ± 4.0&¥ (2.4-29.3) |
1.8 ± 0.5 (0.4-3.9) |
N.D. |
IPF, idiopathic pulmonary fibrosis; Sar, sarcoidosis; CVD-IP, collagen vascular disease with interstitial pneumonia; HV, healthy volunteers; N.D., not determined
All data were shown as mean ± SEM.
"p < 0.0001 v.s. HV, *p < 0.005 v.s. HV, ∫p < 0.05 v.s. HV
†p < 0.0005 v.s. CVD-IP, &p < 0.005 v.s. CVD-IP
$p < 0.005 v.s. Sar, #p < 0.05 v.s. Sar
§p < 0.0001 v.s. IPF, ¥p < 0.001 v.s. IPF, ‡p < 0.005 v.s. IPF, £p < 0.05 v.s. IPF