Table 1.
Top genes upregulated in CD16+ compared to CD16- Mo
| CD16+ Mo AU | |||||
| Gene Symbol | CD16+/CD16- Ratio | p-value | Mean | SD | GeneTitle |
| FCGR3A | 20,1 | 0,000 | 36975 | 6660 | Fc fragment of IgG, low affinity IIIa, receptor for (CD16) |
| CDKN1C | 18,4 | 0,000 | 23838 | 5132 | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| MTSS1 | 5,7 | 0,000 | 12285 | 2678 | metastasis suppressor 1 |
| SIGLEC10 | 4,8 | 0,000 | 10657 | 3068 | sialic acid binding Ig-like lectin 10 |
| IFITM1 | 4,5 | 0,026 | 13823 | 10613 | interferon induced transmembrane protein 1 (9–27) |
| HMOX1 | 3,5 | 0,000 | 16791 | 4339 | heme oxygenase (decycling) 1 |
| TAGLN | 3,2 | 0,000 | 11950 | 3480 | Transgelin |
| TCF7L2 | 3,0 | 0,000 | 16772 | 4608 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| MS4A7 | 2,8 | 0,000 | 22645 | 6376 | membrane-spanning 4-domains, subfamily A, member 7 |
| CSF1R | 2,8 | 0,000 | 22838 | 6537 | colony stimulating factor 1 receptor |
| NAP1L1 | 2,8 | 0,000 | 34370 | 5546 | nucleosome assembly protein 1-like 1 |
| IFITM2 | 2,5 | 0,000 | 58835 | 17536 | interferon induced transmembrane protein 2 (1-8D) |
| SOD1 | 2,5 | 0,000 | 11300 | 2491 | superoxide dismutase 1 |
| IFITM3 | 2,5 | 0,022 | 40793 | 15947 | interferon induced transmembrane protein 3 (1-8U) |
| LST1 | 2,5 | 0,000 | 42904 | 13661 | leukocyte specific transcript 1 |
| CX3CR1 | 2,4 | 0,041 | 25882 | 11806 | chemokine (C-X3-C motif) receptor 1 |
| LILRB1 | 2,4 | 0,000 | 15534 | 4951 | leukocyte immunoglobulin-like receptor, subfamily B, member 1 |
| PSCDBP | 2,3 | 0,000 | 12459 | 2539 | pleckstrin homology, Sec7 and coiled-coil domains, binding protein |
| ITGAL | 2,3 | 0,000 | 13269 | 3384 | integrin, alpha L (antigen CD11A) |
| C6orf187 | 2,3 | 0,022 | 14752 | 5263 | chromosome 6 open reading frame 187 |
| KLF2 | 2,3 | 0,000 | 23783 | 7614 | Kruppel-like factor 2 (lung) |
| WARS | 2,3 | 0,000 | 18466 | 5567 | tryptophanyl-tRNA synthetase |
| MAFB | 2,3 | 0,000 | 16707 | 5853 | v-maf musculoaponeurotic fibrosarcoma oncogene homolog B |
| GCH1 | 2,2 | 0,022 | 10956 | 3586 | GTP cyclohydrolase 1 (dopa-responsive dystonia) |
| CD97 | 2,2 | 0,000 | 10566 | 3203 | CD97 antigen |
| CTSC | 2,2 | 0,000 | 10079 | 2619 | cathepsin C |
| PIK3AP1 | 2,1 | 0,000 | 16825 | 4941 | phosphoinositide-3-kinase adaptor protein 1 |
| 2,1 | 0,000 | 15859 | 4883 | molecule possessing ankyrin repeats induced by lipopolysaccharide | |
| LYN | 2,1 | 0,000 | 19388 | 3520 | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog |
| BCL2A1 | 2,1 | 0,022 | 11110 | 5056 | BCL2-related protein A1 |
| PECAM1 | 2,0 | 0,000 | 22679 | 7106 | platelet/endothelial cell adhesion molecule (CD31 antigen) |
Shown are differentially expressed genes (>2-fold higher in CD16+ compared to CD16- Mo) with the highest expression levels (>10,000 AU). AU, arbitrary units.