Table 2.
Top genes upregulated in CD16- compared to CD16+ Mo
| CD16- Mo AU | |||||
| Gene Symbol | CD16+/CD16- Ratio | p-value | Mean | SD | GeneTitle |
| S100A12 | 0,1 | 0,000 | 32609 | 4915 | S100 calcium binding protein A12 (calgranulin C) |
| CSPG2 | 0,2 | 0,000 | 44600 | 1191 | chondroitin sulfate proteoglycan 2 (versican) |
| CD14 | 0,2 | 0,000 | 29424 | 2503 | CD14 antigen |
| CD36 | 0,2 | 0,000 | 10283 | 2743 | CD36 antigen (collagen type I receptor, thrombospondin receptor) |
| CD99 | 0,2 | 0,000 | 11219 | 925 | CD99 antigen |
| DREV1 | 0,3 | 0,000 | 16902 | 2260 | DORA reverse strand protein 1 |
| CSF3R | 0,3 | 0,000 | 15383 | 2884 | colony stimulating factor 3 receptor (granulocyte) |
| FLJ22662 | 0,3 | 0,000 | 24777 | 3886 | hypothetical protein FLJ22662 |
| MS4A6A | 0,3 | 0,000 | 17295 | 2171 | membrane-spanning 4-domains, subfamily A, member 6A |
| ITGAM | 0,3 | 0,000 | 10344 | 2182 | integrin, alpha M (complement component receptor 3) |
| SELL | 0,3 | 0,038 | 18878 | 6604 | selectin L (lymphocyte adhesion molecule 1) |
| CRTAP | 0,4 | 0,000 | 13026 | 934 | cartilage associated protein |
| S100A9 | 0,4 | 0,000 | 91116 | 15677 | S100 calcium binding protein A9 (calgranulin B) |
| GPX1 | 0,4 | 0,000 | 35555 | 1707 | glutathione peroxidase 1 |
| PLP2 | 0,4 | 0,000 | 10014 | 1672 | proteolipid protein 2 (colonic epithelium-enriched) |
| S100A8 | 0,4 | 0,000 | 114633 | 17191 | S100 calcium binding protein A8 (calgranulin A) |
| PPBP | 0,4 | 0,025 | 10279 | 3787 | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| FPR1 | 0,4 | 0,000 | 23743 | 4367 | formyl peptide receptor 1 |
| EGFL5 | 0,4 | 0,000 | 10378 | 1126 | EGF-like-domain, multiple 5 |
| MNDA | 0,4 | 0,000 | 26939 | 7235 | myeloid cell nuclear differentiation antigen |
| KCTD12 | 0,4 | 0,000 | 21488 | 1640 | potassium channel tetramerisation domain containing 12 |
| DKFZp434L142 | 0,4 | 0,000 | 10904 | 1594 | hypothetical protein DKFZp434L142 |
| GRN | 0,5 | 0,000 | 22341 | 2163 | granulin |
| LYZ | 0,5 | 0,038 | 86499 | 26260 | lysozyme (renal amyloidosis) |
| APLP2 | 0,5 | 0,000 | 23441 | 2191 | amyloid beta (A4) precursor-like protein 2 |
| ALDH2 | 0,5 | 0,000 | 14898 | 1814 | aldehyde dehydrogenase 2 family (mitochondrial) |
| HIF1A | 0,5 | 0,000 | 14221 | 3447 | hypoxia-inducible factor 1, alpha subunit |
| TALDO1 | 0,5 | 0,000 | 21276 | 2781 | transaldolase 1 |
| IRF2BP2 | 0,5 | 0,000 | 21329 | 4404 | interferon regulatory factor 2 binding protein 2 |
| EVI2A | 0,5 | 0,000 | 10200 | 1342 | ecotropic viral integration site 2A |
| AMICA | 0,5 | 0,000 | 10160 | 945 | adhesion molecule AMICA |
| DPYD | 0,5 | 0,000 | 10049 | 1957 | dihydropyrimidine dehydrogenase |
Shown are differentially expressed genes (>2-fold higher in CD16- compared to CD16+ Mo) with the highest expression levels (>10,000 AU). AU, arbitrary units.