Fig. 3.

Regional effects of age on local GM volume rendered onto surface of spatially normalised grey matter. (a) Mean local GM volume in mm³. (b) Decrease in local GM volume in mm³ per year. (c) Voxel-wise T-scores for decrease in local GM volume with age, (T-score > 1.6, corresponding to a descriptive P-value threshold of P < 0.05). (d) Voxel-wise standard error (in mm³) calculated from the square root of the sum of the squares of the difference between the full fitted model and the GM volume data divided by the number of degrees of freedom. Although sub-cortical regions are visible in the medial and inferior views these were not included in the analyses and have therefore been set to the minimum value on the colour scale.