Table 4. Evaluation of predictions supported by experimental data at different threshold level.
Threshold level | Sensitivity (%) | Specificity (%) | Accuracy (%) | Number of missed residues (missed residues index) |
0 | 42.9 | 73.7 | 70.8 | 28 (R58, K80, D87, A109, C138, Y199, Y203, F204, L234, L237, E238, A241, E257, L259, A260, T261, V264, R268, V271, D383, K386, D398, E409, E461, S463, N479, A480, R501) |
1 | 81.6 | 79.2 | 79.4 | 9 (Y203, L234, L237, E238, A241, A260, N479, A480, R501) |
2 | 93.9 | 83.4 | 84.4 | 3 (L237, E238, N479) |
The threshold represents the allowed separation distance in number of residues along the primary sequence between predicted and reported residues. The predicted residues are for all three states and include pivot, messenger, and anchor residues.