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. 2000 Jul 1;321(7252):13–17. doi: 10.1136/bmj.321.7252.13

Table 2.

Stroke by age, systolic blood pressure, and cholesterol concentration according to treatment with aspirin. Figures are numbers of events/person years at entry in each stratum with rates per 1000 person years in parentheses and relative risks corrected for other risk factors

Aspirin (only) Placebo Relative risk Interaction P value
Age (years):
  45-49 0/1447 (0.0) 1/1502 (0.7) NA 0.85
 50-54 3/1905 (1.6) 0/1899 (0.0) NA
 55-59 4/1663 (2.4) 11/1812 (6.1) 0.40
 60-64 7/1811 (3.9) 9/1756 (5.1) 0.99
 65-69 4/1279 (3.1) 5/1102 (4.5) 0.59
Systolic blood pressure (mm Hg):
  <130 2/2688 (0.7) 6/2687 (2.2) 0.41 0.006
 130-145 2/2663 (0.8) 10/2582 (3.9) 0.21
 >145 14/2754 (5.1) 10/2802 (3.6) 1.42
Cholesterol concentration (mmol/l):
  <5.9 3/2808 (1.1) 12/2837 (4.2) 0.20 0.036
 5.9-6.7 7/2674 (2.6) 8/2345 (3.4) 0.90
 >6.7 8/2471 (3.2) 6/2748 (2.2) 1.53

NA: no events in one treatment group.