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. 2009 Jun 23;94(9):3521–3529. doi: 10.1210/jc.2009-0212

Figure 3.

Figure 3

Potential regulators of thyroid hormone action. A, Expression of DIO2 and DIO3 is decreased in liver of obese subjects. B, DIO1 activity is not significantly altered in obese vs. lean humans. Expression of PPARGC1A (C) and LEPR (D) isoforms, as determined by PCR, was decreased in subjects with obesity (striped bars) and T2DM (black bars). Mean ± sd is shown in bar graphs. *, P < 0.05.