Table 3.

Recovery of C. trachomatis MoPn from the lungs of mice following the i.n. challenge

		Immunization	Weight of	Median IFU (range) recovered
Antigen	Adjuvant	route	lungs (g)a	from lungs × (106)
Ct-rMOMP	CpG+Montanide	i.m.+s.c	0.29±0.06b	1.5 (0.0003 – 6,029) d
Ct-nMOMP	CpG+Montanide	i.m.+s.c	0.23±0.03 b,c	0.02 (0.003 – 0.2) d,e
Ng-rPorB	CpG+Montanide	i.m.+s.c	0.35±0.04	3,799 (10 – 18,534)
Live Ct-MoPn	-	i.n.	0.24±0.03 b	0 (0 – 0.0005) d,ef
MEM-0	-	i.n.	0.36±0.03	6,071 (1,899 – 13,339)

^aThe values are means ± 1 SD.

^bP<0.05 as determined by the Student t test compared to the mice immunized with Ng-rPorB or MEM-0.

^cP<0.05 as determined by the Student t test compared to the Ct-rMOMP immunized group.

^dP<0.05 as determined by the Mann-Whitney U test compared to the Ng-rPorB or MEM-0 immunized groups.

^eP<0.05 as determined by the Mann-Whitney U test compared to the mice immunized with Ct-rMOMP.

^fP<0.05 as determined by the Mann-Whitney U test compared to the Ct-nMOMP immunized group.