Figure 1.

DPPI is expressed in enamel organ. Mouse molars were harvested at defined time-points and subjected to real-time PCR analysis with DPPI specific primers. Expression was quantified at days 3, 5, 7, 9, and 11, where day 3 represents early-secretory-stage and day 11 represents maturation-stage enamel organ. Data represent measurements of 6 individual mice per time-point, with each mouse repeated in triplicate (n = 6). Results are presented as fold-increase in expression over day 3 and normalized to EF1α1 mRNA expression. DPPI expression increased dramatically, with an 11.38 ± 1.78-fold increase at the maturation stage over the secretory stage (*p < 0.05; **p < 0.001). Data are presented as mean ± SEM.