Figure 1. Enrichment limited to the pre-weaning period improves performance in the Morris water maze (MWM) to a level equivalent to life-long enrichment.

Average MWM latencies across 7 training days of non-enriched mice (NN, solid black, n = 10), mice enriched from weaning (NE, solid red, n = 16), enriched from birth until weaning (EN, dashed black, n = 7) and enriched from birth into adulthood (EE, dashed red, n = 7). Mice receiving enrichment performed significantly better across the 7 training days relative to non-enriched mice (Mixed model ANOVA, F(3, 36) = 8.48, p<0.001; see text).