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. Author manuscript; available in PMC: 2010 Aug 15.
Published in final edited form as: Eur J Pharmacol. 2009 Jun 17;616(1-3):31–37. doi: 10.1016/j.ejphar.2009.06.012

Fig. 6.

Fig. 6

NDGA analogs displayed differential effects on TGF-β mediated transcription. Panc-1 cells were transiently transfected with luciferase reporters CAGA12-Luc and pRL-null. Cells were treated with 10 ng/ml TGF-β and different amounts of NDGA analogs (1, DMSO control; 2, NDGA or NDGA analogs 20µM; 3, NDGA or NDGA analogs 50µM.) for 6 hours before harvested for dual luciferase assay. A) Compound 1 was less potent than NDGA. B) Compound 2 was less potent than NDGA. C) Compound 3 lost the inhibitory effects of NDGA.