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. Author manuscript; available in PMC: 2010 Aug 15.
Published in final edited form as: Eur J Pharmacol. 2009 Jun 17;616(1-3):31–37. doi: 10.1016/j.ejphar.2009.06.012

Fig. 7.

Fig. 7

NDGA analogs can be structurally refined to achieve higher potency. Panc-1 cells were transiently transfected with luciferase reporters CAGA12-Luc and pRL-null. Cells were treated with 10 ng/ml TGF-β and different amounts of NDGA analogs (1 DMSO; 2, NDGA analogs 20µM; 3, NDGA analogs 50µM.) for 6 hours before harvested for dual luciferase assay. A) Compound 1.1 was more potent than compound 1. B) Compound 1.2 was more potent than compound 1. C) Compound 1.3 had similar potency as compound 1.