Table 1.
Change in the activity of transporter proteins in syncytiotrophoblast microvillous (MVM) and basal (BM) plasma membranes in fetal growth restriction
| Transporter | MVM Change | BM Change | Reference |
|---|---|---|---|
| System A (alanine/glycine) | Decrease | No change | (Glazier et al. 1997; Jansson et al. 2002) |
| Leucine | Decrease | Decrease | (Jansson et al. 1998) |
| Lysine | No change | Decrease | (Jansson et al. 1998) |
| Na+-dependent taurine | Decrease | No change | (Norberg et al. 1998; Roos et al. 2004) |
| Na+-independent taurine | No change | Decrease | (Norberg et al. 1998) |
| GLUT1 (glucose) | No change | No change | (Jansson et al. 1993; Jansson et al. 2001) |
| Na+/K+-ATPase | Decrease | No change | (Johansson et al. 2003) |
| Ca2+ (ATP dependent) | (not present) | Increase | (Strid et al. 2003) |
| Na+/H+ exchanger | Decrease | Activity not present | (Glazier et al. 1997; Johansson et al. 2002) |
| Lipoprotein lipase (cf FFA transport) | Decrease | Not known | (Magnusson et al. 2004) |
| H+/lactate transporter | No change | Decrease | (Settle et al. 2006) |