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. 2009 May 26;587(Pt 14):3523–3538. doi: 10.1113/jphysiol.2009.172577

Figure 1. Effects of α,β-me-ATP and the P2 purinoreceptor antagonist PPADS on firing of muscle-mucosal afferents.

Figure 1

PPADS (30 μm) did not affect either stretch-induced firing of bladder mechanoreceptors (n= 6, N= 6) (A) or stretch-induced responses (N= 6) (B). C, averaged data of the effects of P2X-preferring agonist α,β-me-ATP (100 μm) on muscle-mucosal afferents in control (n= 9, N= 8) or in the presence of PPADS (30 μm, n= 7, N= 5). *P < 0.001. D, averaged data of the effects of PPADS (30 μm, n= 6, N= 6) on firing of muscle-mucosal afferents evoked by stroking of their transduction sites with a von Frey hair (1 mN).