Table 2.

Mediators of the right ventrolateral prefrontal cortex (vlPFC) relationship with reappraisal success in whole-brain search

	Coordinates			Correlation		a path		b path		ab path		Conjunction (Num. Vox)
Name	x	y	z	r	p	Z	p	Z	p	Z	p	P<.005	P<.01	P<.05
Positive mediators
ITG (R)	58	−38	−22	0.48	0.009	4.22	<.001	3.22	0.001	3.15	0.002	5	7	41
NAC/SGACC	3	21	−9	0.49	0.007	3.60	<.001	3.25	0.001	3.34	0.001	4	9	85
Isth Cing	−3	−41	4	0.48	0.009	4.02	<.001	3.05	0.002	3.50	0.001	2	4	34
Cau (R)	21	7	22	0.44	0.020	4.23	<.001	2.89	0.004	3.13	0.002	1	2	6
DMPFC (R)	24	41	40	0.52	0.004	4.53	<.001	2.92	0.004	3.41	0.001	1	8	32
PreSMA/SFG	−14	7	63	0.52	0.004	4.92	<.001	3.79	<.001	3.79	<.001	9	16	159
SFG (R)	24	21	58	0.44	0.020	3.81	<.001	3.21	0.001	2.98	0.003	1	7	51
Precuneus	−3	−52	68	0.50	0.005	4.50	<.001	3.09	0.002	3.14	0.002	1	4	27
Negative mediators
AMY (L)	−28	−3	−32	−0.58	0.001	4.77	<.001	−5.69	<.001	−3.92	<.001	6	7	42
AMY (R)	14	−7	−22	−0.56	0.002	5.72	<.001	−4.31	<.001	−2.95	0.003	1	20	104
LOFC (R)	48	24	−18	−0.47	0.010	5.20	<.001	−3.13	0.002	−3.02	0.003	1	1	17
VAINS (L)	−38	10	−14	−0.44	0.020	3.33	0.001	−3.30	0.001	−3.47	0.001	1	5	29
Subthalamus	−3	−10	−4	−0.29	0.130	2.97	0.003	−3.00	0.003	−2.93	0.003	1	1	3
RACC	−7	17	22	−0.37	0.050	3.28	0.001	−3.46	0.001	−3.29	0.001	2	4	18

Note. These results complement focused searches within a priori subcortical ROIs. For this exploratory analysis, we considered voxels to be significant mediators if statistical significance reached p < .005 in each of the three following effects: a path) Correlation between vlPFC and voxel activity; b path) Correlation between voxel and reported emotional experience, controlling for vlPFC; and a*b path) Significant indirect effect, whose magnitude is the product of (a) and (b). All statistics were assessed with bootstrapping (1,000 samples) at each voxel. These regions were subjected to subsequent multivariate clustering analysis for grouping into networks. Correlation refers to correlation with reported experience.