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Effects of MnTE-2-PyP on nitrotyrosine formation in the lung. No positive staining for nitrotyrosine was observed in lung tissues obtained from sham mice (a). In contrast, tissue sections obtained from carrageenan-treated mice at 4h after carrageenan administration demonstrate positive staining for nitrotyrosine (see arrows b) and this was blocked by MnTE-2-PyP (c). Figure is representative of at least 3 experiments performed on different experimental days.
