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. Author manuscript; available in PMC: 2010 Mar 15.
Published in final edited form as: Cancer. 2009 Mar 15;115(6):1142–1153. doi: 10.1002/cncr.24134

Table 1.

Self-report Sexual Function Measures, their Domains, Reliability and Validity, and Citations by Cancer Site

Instrument Name Domains & Internal Consistency Reliability and Validity Cancer site and references
Arizona Sexual Experience Scale (ASEX)
McGahuey, et al., 2000
Sex drive
Arousal
Lubrication/Erection
Ability to reach orgasm
Satisfaction from orgasm
Overall alpha = .91
Concurrent, construct
Female cancers
- Mathias, et al., 2005
Breast
- Mathias, et al. 2006
Brief Index of Sexual Functioning for Women (BISF-W)
Taylor, et al., 1994; Mazer, et al., 2000
Sexual interest/desire
Sexual activity
Sexual satisfaction
Internal consistencies of subscales = .39 - .74; overall alpha = .83
Test-retest r = .68 – .78
Concurrent, construct
Breast or gyn/I-Iib
- Scott, et al., 2004
Gynecologic
- Du, et al., 2005
Prostate (spouses)
- Soloway, et al., 2005
Brief Sexual Function Questionnaire for Men (BSFQ)
Reynolds et al, 1988
Sexual activity/performance
Interest
Satisfaction
Physiological competence
Guttman total test-retest reliability = .94
Concurrent, construct
Prostate
- Soloway, et al., 2005
Brief Sexual Function Inventory (BSFI)
O’Leary, et al., 1995
Interest
Function
Ejaculation
Problems/satisfaction
Internal consistency of domains alpha = .62 - .92
Test-retest r = .68 - .70
Concurrent, construct
Prostate
- Bradley, et al., 2004
- Deliveliotis, et al., 2004
- Rajagopal, et al.,2003
- Valicenti, et al., 2002
- Chen, et al., 2001
- Valicenti, et al., 2001
- Krupski, et al., 2000
- Hong, et al., 1999
Changes in Sexual Functioning Questionnaire (CSFQ)
Clayton et al., 1997a, 1997b; Keller, et al., 2006
Desire/Frequency
Desire/Interest
Arousal/Excitement
Orgasm/Completion
Pleasure
Internal consistency of domains = .64 - .80
Test-retest r = 0.45 – 1.00
Construct
All female cancer sites
- Barton, et al., 2007
Gynaecological cancer
- Lagana, et al., 2005
- Caldwell, et al., 2003
Derogatis Interview for Sexual Functioning-Self Report (DISF-SR)
Derogatis, 1997
Cognition/fantasy
Arousal
Sexual behavior
Orgasm
Drive
Internal consistency alpha of domains = .74 – 0.80 Cervical cancer
- Schroder, et al., 2005
Derogatis Sexual Functioning Inventory (DSFI)
Derogatis, 1979
Information
Experience
Drive
Attitudes
Psychological
Distress
Gender Role
Fantasy
Body Image
Sexual satisfaction
Frequency of activity
Internal consistency of domains alpha = .56 - .97
Test-retest.61 - .96
Construct
All sites
- Ananth, et al., 2003
Breast
- Young-McCaughan, 1996
Cervix
- Grumann, et al., 2001
- Schroder, et al., 2005
Head and neck
- Monga, et al., 1997
Hematologic
- Marks, et al., 1996
Erectile Dysfunction
- Effect on Quality of Life (ED-EQoL)
MacDonagh, et al. 2004
Erectile dysfunction Internal consistency alpha = .94
Construct
(Discriminant: Ferguson’s delta = .86)
Prostate
- Meyer, et al., 2003
Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS)
Althof, et al., 1999
Erectile dysfunction Internal consistency (patient) alpha = .90; (partner) alpha = .76
Test-retest (patient) r = .98; (partner) r = .83
Content
Prostate
- Ramsawh, et al., 2005
- Montorsi, et al., 2004
Female Sexual Function Index (FSFI)
Rosen et al., 2000
Wiegel et al., 2005
Desire
Arousal
Lubrication
Orgasm
Satisfaction
Pain
Internal consistency alpha > .90
Test-retest r = 0.79-0.86
Construct
Bladder
- Bhatt, et al., 2006
Breast
- Schover, et al., 2006
- Speer, et al., 2005
Cervix
- Frumovitz, et al., 2005
- Schroder, et al., 2005
Gynecologic
- Carter, et al., 2005
Rectal
- Hendren, et al., 2005
- Jayne, et al., 2005
Vulvar 46,47
- Likes, et al., 2007a
- Likes, et al., 2007b
Golombok Rust Inventory of Sexual Satisfaction (GRISS)
Rust, et al., 1985, 1986; ter Kuile, et al., 1999; van Lankveld, et al., 1999; 2003
Erectile dysfunction
Premature ejaculation
Anorgasmia
Vaginismus
Noncommunication
Infrequency
Male and Female:
 Avoidance
 Nonsensuality
 Dissatisfaction
Internal consistency of subscales alpha = .72 - .98
Test-retest of subscale r = .72 - .90
Predictive, construct
Breast
- Onen Sertoz, et al., 2004
Testicular
- Sheppard, et al., 2001
International Continence Society questionnaire (male and sex subscales) (ICS)
Donovan, et al., 2000
Erectile function Internal consistency of subscales alpha = .69 - .91
Test-retest of symptom score r = .78; problem score r = .83
Criterion, construct
Prostate
- Henderson, et al. 2006
- Rozet, et al., 2005
- Selli, et al., 2004
- Gacci, et al., 2003
- Hara, et al., 2003
Index of Female Sexual Function (IFSF-modified)
- Kaplan, et al. 1999
Zippe, et al. 2004
Free of pain during intercourse
Degree of vaginal Lubrication
Overall sexual desire and interest
Ability to achieve orgasm
Overall sexual satisfaction
Internal consistency alpha = .80 - .90
Test retest of subscales r = .71 - .76; total scale r = .70
Construct
Bladder
- Zippe, et al., 2004
International Index of Erectile Function Sexual Health Inventory for Men (IIEF-15, SHIM, IIEF-5)
Rosen, et al., 1997, 1999, 2002; Rhoden, et al., 2002; Cappelleri et al., 2005
Erectile function
Orgasm
Desire
Intercourse satisfaction
Overall satisfaction
IIEF-5
Erectile function
Intercourse satisfaction
Internal consistency of domains alpha = 0.73–0.99
Test–retest of domains r = 0.64–0.84
Construct
Bladder
- Davila, et al., 2007
- Wang, et al., 2007
- Columbo, et al., 2004
Prostate
- Cesaretti, et al., 2007
- Chang, et al., 2007
- Davison, et al., 2007
- Incrocci, et al., 2007
- Kava, et al., 2007
- Kohler, et al., 2007
- Lee, et al., 2007
- Lu, et al., 2007
- Madeb, et al., 2007
- Mattei, 2007
- Matthew, et al, 2007
- Papadoukakis, et al., 2007
- Wille, et al., 2007
- Zagar, et al., 2007
- Bannowsky, et al., 2006
- Chaplin, et al., 2006
- Col, et al., 2006
- Incrocci, et al., 2006
- Kim, et al., 2006
- Long, et al., 2006
- Latini, et al., 2006 (a)
- Latini, et al., 2006 (b)
- Ponholzer, et al., 2006
- Salonia, et al., 2006
- Titta, et al., 2006
- Wilke, et al., 2006
- Zucchi, et al., 2006
- Bannowsky, et al., 2005
- Bellina, et al., 2005
- Canada, et al., 2005
- De Lorenzo, et al., 2005
- Dinelli, et al., 2005
- Karakiewicz, et al., 2005
- Mabjeesh, et al., 2005
- Menon, et al., 2005
- Matzkin, et al., 2005
- Merrick, et al., 2005
- Mulhall, et al., 2005
- Ohebshalom, et al., 2005
- Pompeu, et al., 2005
- Porpiglia, et al., 2005
- Ponholzer, et al., 2005
- Rozet, et al., 2005
- Shindel, et al., 2005
- Trinchieri, et al., 2005
- Yatim, 2005
- Alduais, et al., 2004
- Colombo, et al., 2004
- Davison, et al., 2004
- Fujioka, et al., 2004
- Montorsi, et al., 2004
- Ogura, et al., 2004
- Raina, et al., 2004
- Saidi, et al., 2004
- Anastasiadis, et al., 2003
- Gacci, et al., 2003
- Hara, et al., 2003
- Incrocci, et al., 2003
- Lee, et al., 2003
- Menon, et al., 2003
- Penson, et al., 2003
- Raina, et al., 2003
- Noldus, et al., 2002
- Schover, et al., 2002a
- Schover, et al., 2002b
- Merrick, et al., 2001
- Incrocci, et al., 2001
- Matzkin, et al., 2001
- Saito, et al., 2001
- Blander, et al. 2000
- Kedia, et al., 1999
Testicular
- Wiechno, et al., 2007
- Lackner, et al., 2005
Rectal
- He & Pu, 2005
- Hendren, et al., 2005
- Jayne, et al., 2005
Medical Outcomes Study (MOS) Sexual Functioning Scale (MOS-SFS)
Sherbourne, 1992, in Stewart & Ware (eds.), 1992; McHorney, et al., 1994; Hays, et al.,1993
Sexual activity
Difficulty becoming aroused
Difficulty relaxing/enjoying sex
Difficulty achieving orgasm
Internal consistency (men) alpha = .90; (omen) r = .92
Construct
Breast
- Burwell, et al., 2006
- Broeckel, et al., 2002
Head and Neck
- Siston, et al., 1997
UCLA Prostate Cancer Index-Sexual Function/Sexual Bother (UCLA PCI-SF/SB)
Lubeck, et al., 1997 Litwin, et al., 1998, 2002; Karakiewicz, et al. 2003; Krongrad, et al 1998
UCLA Prostate Cancer Index + [Dutch] Sexual Activities module
Incrocci, et al., 2001; Korfage, et al., 2003
UCLA Expanded Prostate Index Composite (EPIC)
Wei, et al., 2000
Japanese adapted EPIC
Takegami, et al., 2005; Kakehi, et al., 2007; Namiki, et al., 2007a
Sexual function
Sexual bother
Internal consistency of subscales > .78
Cross-cultural validity, construct
Prostate
- Anger, et al., 2007
- Arredondo, et al., 2007
- Ash, et al., 2007
- Campbell, et al., 2007
- Dearnaley, et al., 2007
- Frank, et al., 2007
- Kakehi, et al., 2007
- Kato, et al., 2007
- Kübler, et al., 2007
- Litwin, et al., 2007
- Namiki, et al., 2007b
- Namiki, et al., 2007c
- Penedo, et al., 2007
- Stevens, et al. 2007
- Van der Wielen, et al., 2007
- Ball, et al., 2006
- Dalkin, et al., 2006
- Ishihara, et al., 2006
- Joseph, et al., 2006
- Miller, et al., 2006
- Montgomery, et al., 2006
- Namiki, et al., 2006
- Newton, et al., 2006
- Pinkawa, et al., 2006a
- Pinkawa, et al., 2006b
- Sanderson, et al., 2006
- Tseng, et al., 2006
- Wagner, et al., 2006
- Dahn, et al., 2005
- Descazeaud, et al., 2005
- Jayadevappa, et al., 2005
- Korfage, et al., 2005
- Krupski, et al., 2005
- Link, et al., 2005
- Penson, et al., 2005
- Soderdahl, et al., 2005
- Steginga, et al., 2005
- Wiygul, et al., 2005
- Yang, et al., 2005
- Campbell, et al., 2004
- Dahn, et al., 2004
- Descazeaud, et al., 2004
- Hoffman, et al.,
- Hollenbeck, et al., 2004
- Hu, et al., 2004
- Jenkins, et al., 2004
- Lepore, et al., 2004
- Merrick, et al., 2004
- Namiki, et al., 2004a
- Namiki, et al., 2004b
- Schover, et al., 2004
- Su, et al., 2004
- Cooperberg, et al., 2003
- Downs, et al., 2003
- Hollenbeck, et al., 2003
- Korfage, et al., 2003
- Krahn, et al., 2003
- Oefelein, 2003
- Penson, et al., 2003
- Bacon, et al., 2002
- Hollenbeck, et al.,
- 2002
- Katz, et al., 2002
- Smith, et al., 2002
- Valicenti, et al., 2002
- Wei, et al., 2002
- Chen, et al., 2001
- Davis, et al., 2001
- Fulmer, et al., 2001
- Kupelian, et al., 2001
- Litwin, et al., 2001
- Lubeck, et al., 2001a
- Lubeck, et al., 2001b
- Madalinska, et al., 2001a
- Madalinska, et al., 2001b
- Penson, et al., 2001
- Pietrow, et al., 2001
- Schapira, et al., 2001
- Brandeis, et al., 2000
- Gralnek, et al., 2000
- Potosky, et al., 2000
- Sanchez-Ortiz, et al., 2000
- Smith, et al., 2000
- Litwin, et al., 1999
- Perrotte, et al., 1999
- Krongrad, et al., 1998
- Litwin, et al., 1998
- Yarbro, et al., 1998
Psychological Impact of Erectile Dysfunction (PIED)
Latini, et al., 2002
Sexual experience
Emotional life
Internal consistency of subscales alpha = .72 - .91
Test-retest of subscales r = .66 - .76
Construct
Prostate
- Penson, et al., 2003
Sapporo Medical University Sexual Function Questionnaire (SMUSFQ)
Kato, et al., 1999
Sexual desire
Erectile function
Satisfaction after sex
Sexual activity
Overall satisfaction
Reliability not reported
Construct
Prostate
- Yoshimura, et al., 2004
- Yoshimura, et al., 2003
- Miyao, et al., 2001
- Arai, et al., 1999
- Shibuya, et al., 1997
Sexual Adjustment Questionnaire RTOG Modified Sexual Adjustment Questionnaire (SAQ-H)
Waterhouse, et al., 1986; Bruner, et al., 1998
Activity
Arousal
Libido
Orgasm
Satisfaction
Relationships
Techniques
Sexual dysfunction
Test-retest (females) r = 0.67
Construct
Prostate
- Feigenberg, et al., 2005
- Bruner, et al., 2004
- Bruner, et al., 1998
Gynecologic
- Ratliff, et al., 1996
Sexual Activity Questionnaire (SAQ)
Thirlaway, et al., 1996
Frequency of sexual activity
Sexual interest/desire
Arousal/vaginal dryness
Sexually related pain
Internal consistency alpha = .56 - .88
Test-retest kappa = .50 – 1.0
Breast
- Ganz, et al., 2003
- Ganz, et al., 2002
- Fobair, et al., 2001
Ovarian
- Carmack Taylor, et al., 2004
Gynecologic
- Wenzel, et al., 2002
Sexual Arousability Inventory (SAI)
Hoon, et al., 1976
Sexual arousability Internal consistency alpha = .91 - .92
Split half r = .92
Content, construct
Breast
- Wellisch, et al., ,1996
- Wellisch, et al., ,1992
- Wellisch, et al., 1991
Sexual Adjustment Questionnaire (SAQ-modified)
O’Farrell, et al., 1997
Overall satisfaction
Frequency of intercourse
Discrepancy between desire and actual frequency
Communication
Ease of refusal
Satisfaction with specific aspects
Satisfaction with privacy and context
Sexual dysfunction
Reliability not reported
Content, construct
Prostate
- Soloway, et al., 2005
Sexual Beliefs and Information Questionnaire (SBIQ)
Adams, et al., 1996
Time/patience
Stress/pressure
Aging
Sexual satifaction
Other/basic knowledge
Internal consistency total alpha = .81; factors alpha = .42 - .93
Test-retest r = .82
Content
Gynecologic
- Brotto, et al., 2007
Sexual Function After Treatment for Gynecologic Cancer (SFAGIS)
Bransfield, et al., 1984
Fears about sexual activity
Partner fears about sexual activity
Initiation of activity
Vaginal condition
Vaginal lubrication
Health provider intervention
Desire for sexual information
Changes in sexual activity
Split half r= .80
Kuder-Richardson 20 internal consistency = .76
Content
Gynecologic
- Bruner, et al., 1999
Sexual Function Inventory Questionnaire (SFIQ)
Klotz, et al., 2000
Not reported Reliability and validity not reported Prostate
- Klotz, et al., 2000
Sexual Function Questionnaire (SFQ)
Syrjala, et al., 2000
Sexual activity
Specific problems
Interest
Desire
Arousal
Orgasm
Satisfaction
Masturbation
Relationship
Internal consistency of domains alpha > .80; overall alpha = .94
Criterion, construct
All cancers
- Syrjala, et al., 2000
Hematologic
- Syrjala, et al., 2005
Sexual History Form (SHF)
Schover & Jensen, 1988
Sexual behavior
Frequency
Satisfaction
Reliability on 12 of 28 original items:
Internal consistency (men) alpha = .65
Test-retest (women) r = .92; (men) r = .98
Bladder
- Hart, et al., 1999
Breast
-Greendale, et al., 2001
- Mortimer, et al., 1999
- Makar, et al., 1997
- Schover, et al., 1995
Prostate
- Perez, et al., 2002
Sexual Self-Efficacy
Scales-Erectile
Functioning
Sexual Self-Efficacy
Scales-Female
Functioning
SSES: SSES-EF, SSES-FF
Fichten, et al., 1998; Bailes, et al., 1998
SSES-M
Unidimensional
SSES-F
Interpersonal Orgasm
Individual
Interest/Desire
Sensuality
Individual Arousal
Affection
Communication
Body Acceptance
Refusal
SSES-M
Internal consistency alpha = .86 - .92
Test-retest r = .97-.98
Concurrent, construct
SSES-F
Internal consistency alpha = .93 total; subscales alpha = .70 - .87
Test-retest r = .83 total; subscales r = .50 - .93
Concurrent
Prostate
- Latini, et al., 2006
- Penson, et al., 2003
Sexual Self-Schema
Scale
(SSSS)
Andersen & Cyranowski, 1994
Passionate–romantic Open
Embarrassed–Conservative
Intercorrelations.65 - .80
Construct
Ovarian
- Champion, et al., 2007
- Gershenson, et al., 2007
Prostate
- Schover, et al., 2004
- Jenkins, et al., 2004
- Schover, et al., 2002a
- Schover, et al., 2002b
Gynecologic
- Andersen, et al., 1997
Sexual function-Vaginal changes Questionnaire (SVQ)
Jensen, Klee, Thranov et al. 2004
Sexual interest
Lubrication
Orgasm
Dyspareunia
Vaginal dimensions
Intimacy
Sexual problems of partner
Sexual activity
Sexual satisfaction
Body image
Sexual and vaginal problems
Internal consistency for subscales alpha = .76 - .83
Median kappa (patient/observer) = .80
Construct
Cervix
- Jensen, et al., 2004
- Jensen, et al., 2003
Watts Sexual Function Questionnaire (WSFQ)
Watts, 1982
Not reported Internal consistency alpha = 0.80
Test-retest r = 0.83
Breast
- Rowland, et al., 2000
Prostate
- Basaria, et al., 2002

References for Table 1 are available upon request.