Skip to main content
. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: Gastroenterology. 2009 May;136(5):1806–1817. doi: 10.1053/j.gastro.2009.01.063

Figure 5. Depletion of neutrophils and Kupffer cells after anti-PMN and GdCl3.

Figure 5

(A) MPO-stained neutrophils in the liver from normal rat, rat 6 h after cell transplantation alone, or rat treated with anti-PMN before cell transplantation. Note accumulation of neutrophils after cell transplantation (arrows), including their proximity to hepatocytes as shown in the panel at higher magnification, and their depletion after anti-PMN. Panel B shows cumulative decreases in MPO-positive cells and hepatic MPO activity after various treatments. (C) Shows carbon-containing Kupffer cells in normal rat, and rats 6 h after cell transplantation (arrows), where DPPIV-positive transplanted cells (red color) are present, whereas in animal treated with GdCl3, carbon uptake decreased. (D) Shows cumulative analysis of changes in Kupffer cell activation with fewer Kupffer cells containing carbon after GdCl3.