Table 1.

Sbds interacting proteins identified by mass spectrometry

Ranka	Protein FDRb	Protein listc	Gene symbol	Descriptiond
1	1.61E−144	IPI00427330	SBDS	Shwachman-Bodian-Diamond syndrome protein [Acc: Q9Y3A5]
2	4.75E−38	IPI00020127	RPA1	Replication protein A 70 kDa DNA-binding subunit (RP-A) (RF-A) (Replication factor-A protein 1) (Single-stranded DNA-binding protein) (p70) [Acc: P27694]
3	9.24E−38	IPI00604620	NCL	Nucleolin (Protein C23) [Acc: P19338]
4	2.69E−33	IPI00003918	RPL4	60S ribosomal protein L4 (L1) [Acc: P36578]
5	1.76E−29	IPI00844578	DHX9	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9) [Acc: Q08211]
6	2.55E−28	IPI00479217	HNRPU	Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (Scaffold attachment factor A) (SAF-A) (p120) (pp120) [Acc: Q00839]
7	7.55E−27	IPI00171903	HNRPM	Heterogeneous nuclear ribonucleoprotein M (hnRNP M) [Acc: P52272]
8	3.70E−24	IPI00299573	RPL7A	60S ribosomal protein L7a (Surfeit locus protein 3) (PLA-X polypeptide) [Acc: P62424]
9	5.57E−23	IPI00296337	PRKDC	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460) [Acc: P78527]
10	1.04E−22	IPI00217467	HIST1H1E	Histone H1.4 (Histone H1b) [Acc: P10412]
11	1.58E−21	IPI00030179	RPL7	60S ribosomal protein L7 [Acc: P18124]
12	2.97E−21	IPI00217465	HIST1H1C	Histone H1.2 (Histone H1d) [Acc: P16403]
13	1.53E−18	IPI00549248	NPM1	Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Numatrin) (Nucleolar protein NO38) [Acc: P06748]
14	9.15E−17	IPI00550021	RPL3	60S ribosomal protein L3 (HIV-1 TAR RNA-binding protein B) (TARBP-B) [Acc: P39023]
15	1.75E−16	IPI00329389	RPL6	60S ribosomal protein L6 (TAX-responsive enhancer element-binding protein 107) (TAXREB107) (Neoplasm-related protein C140) [Acc: Q02878]
16	3.36E−16	IPI00012772	RPL8	60S ribosomal protein L8 [Acc: P62917]
17	1.24E−15	IPI00005024	MYBBP1A	Myb-binding protein 1A [Acc: Q9BQG0]
18	2.40E−15	IPI00015953	DDX21	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21) [Acc: Q9NR30]
19	4.65E−15	IPI00555744	RPL14	60S ribosomal protein L14 (CAG-ISL 7) [Acc: P50914]
20	9.02E−15	IPI00008530	RPLP0	60S acidic ribosomal protein P0 (L10E) [Acc: P05388]
21	3.54E−14	IPI00215719	RPL18	60S ribosomal protein L18 [Acc: Q07020]
22	4.82E−13	IPI00008557	IGF2BP1	Insulin-like growth factor 2 mRNA binding protein 1 [Acc: NP_006537]
23	4.82E−13	IPI00024933	RPL12	60S ribosomal protein L12 [Acc: P30050]
24	9.46E−13	IPI00000494	RPL5	60S ribosomal protein L5 [Acc: P46777]
25	3.56E−12	IPI00220834	XRCC5	ATP-dependent DNA helicase 2 subunit 2 (EC 3.6.1.-) (ATP-dependent DNA helicase II 80 kDa subunit) (Lupus Ku autoantigen protein p86) (Ku86) (Ku80) (86 kDa subunit of Ku antigen) (Thyroid-lupus autoantigen) (TLAA) (CTC box-binding factor 85 kDa subunit) [Acc: P13010]
26	3.56E−12	IPI00011253	RPS3	40S ribosomal protein S3 [Acc: P23396]
27	7.01E−12	IPI00465361	RPL13	60S ribosomal protein L13 (breast basic conserved protein 1) [Acc: P26373]

^aPutative Sbds interacting proteins were ranked by descending protein false discovery rate (FDR).

^bFDR corresponds to an adjusted P-value for each prediction in the data set.

^cProtein list numbers represent international protein index (IPI) database references.

^dDescription includes gene accession numbers and names of identified interacting proteins.