Table 4.
The results of a SHARE analysis on 5 SNPs in the TFPI gene. SNPs 1–5 are rs2192824, rs2300412, rs8176597, rs8176612, and rs3771059, respectively. The left table shows 10 haplotypes using all 5 SNPs in the analysis. The right table shows that using SHARE, the association was narrowed down to haplotypes based on rs2192824 and rs2300412
Haplotype | 1 | 2 | 3 | 4 | 5 | Frequency |
1 | 0 | 0 | 0 | 0 | 0 | 0.2254 |
2 | 0 | 0 | 0 | 0 | 1 | 0.0018 |
3 | 0 | 0 | 0 | 1 | 0 | 0.0002 |
4 | 0 | 1 | 0 | 0 | 0 | 0.0593 |
5 | 0 | 1 | 0 | 0 | 1 | 0.2644 |
6 | 0 | 1 | 0 | 1 | 0 | 0.0003 |
7 | 0 | 1 | 1 | 0 | 0 | 0.0515 |
8 | 1 | 0 | 0 | 0 | 0 | 0.2989 |
9 | 1 | 0 | 0 | 0 | 1 | 0.0376 |
10 | 1 | 0 | 0 | 1 | 0 | 0.0605 |
Haplotype | 1 | 2 | Frequency | OR (95% confidence interval) | |
I | 0 | 0 | 0.227 | — | |
II | 0 | 1 | 0.376 | 1.28 (1.02, 1.63) | |
III | 1 | 0 | 0.397 | 1.43 (1.16, 1.87) |