TABLE 4.
GPX Activities in the Lung
| Dietary Selenium (mg/kg diet) | Treatment | n | Se-dependent GPx activity (nmol NADPH/min/mg protein) | Total GPx activity (nmol NADPH/min/mg protein) |
| 0.15 | Control | 4 | 160.8 ± 51.8a | 321 ± 62 |
| Smoke | 4 | 227.8 ± 62.7*a | 305 ± 51 | |
| 0.5 | Control | 4 | 225.1 ± 26.3b | 330 ± 37 |
| Smoke | 4 | 262.6 ± 39.6*b | 346 ± 19 | |
| 2.0 | Control | 4 | 203.6 ± 31.6ab | 299 ± 46 |
| Smoke | 4 | 211.7 ± 49.0*a,b | 302 ± 27 | |
| Results of two way ANOVA (p values) | ||||
| Main effect for selenium | 0.10 | 0.24 | ||
| Main effect for Smoking | 0.05 | 0.96 | ||
| Selenium × Smoking interaction | 0.44 | 0.75 | ||
Note. Results are means ± SEM. Significant differences in smoke-exposed mice for the same selenium level are indicated with an asterisk (*); for differences due to dietary selenium, values with different superscript letters are significantly different (p < 0.05).