Figure 8.

Neurogenic output of INP and apical progenitor divisions as indicated by Tis21-GFP expression. (A–C) Comparison of apical and basal mitoses. Apical divisions were more numerous than basal throughout neurogenesis (A), but basal divisions were more often neurogenic (B). (D–F) Comparison of Tbr2⁺ and highly Pax6⁺ mitoses. Pax6⁺ divisions were more numerous (D), but Tbr2⁺ divisions were more often neurogenic (E). Neurogenic output from INPs was found to be higher than from RGPs, regardless of whether progenitor types were defined by apical or basal division (C) or by transcription factor expression (F).