Table 5.
Cox proportional hazards analyses, liver transplantation (n= 134)*
| Stage/score | HR | 95% CI | P-value | c-statistic |
|---|---|---|---|---|
| IHPBA staging system | ||||
| T1 (n= 39) | Ref. | – | 0.15 | 0.56 |
| T2 (n= 79) | 1.36 | 0.63–2.96 | ||
| T3 (n= 16) | 2.82 | 1.04–7.67 | ||
| CLIP score | ||||
| 0 (n= 35) | Ref. | – | 0.60 | 0.54 |
| 1 (n= 42) | 1.77 | 0.75–4.18 | ||
| 2 (n= 17) | 1.63 | 0.56–4.69 | ||
| 3 (n= 2) | 1.69 | 0.21–13.6 | ||
| BCLC staging system | ||||
| 0 (n= 39) | Ref. | – | 0.28 | 0.54 |
| A1–A3 (n= 63) | 1.34 | 0.60–3.00 | ||
| A4 (n= 32) | 2.02 | 0.84–4.84 | ||
| JIS score | ||||
| 0 (n= 23) | Ref. | – | 0.07 | 0.52 |
| 1 (n= 62) | 3.78 | 1.11–12.9 | ||
| 2 (n= 39) | 3.22 | 0.91–11.4 | ||
| 3 (n= 10) | 5.11 | 1.13–23.1 | ||
| AJCC/UICC staging system | ||||
| T1 (n= 92) | Ref. | – | 0.02 | 0.58 |
| T2 (n= 42) | 2.29 | 1.19–4.42 | ||
| Early HCC prognostic score | ||||
| 0 (n= 34) | Ref. | – | 0.01 | 0.60 |
| 1 (n= 79) | 1.39 | 0.59–3.28 | ||
| 2 (n= 21) | 4.24 | 1.58–11.3 |
*
The Okuda staging system was omitted because observations in stages A (n= 0) and C (n= 1) were too few
HR, hazard ratio; CI, confidence interval; Ref., referent; IHPBA, International Hepato-Pancreato-Biliary Association; CLIP, Cancer of the Liver Italian Programme; BCLC, Barcelona Clinic Liver Cancer; JIS, Japanese Integrated Staging; AJCC/UICC, American Joint Committee on Cancer/International Union Against Cancer, 6th edition; HCC, hepatocellular carcinoma