Table 2.

Demographic, histological and operative variables associated with disease-specific survival in 43 patients undergoing potentially curative resection of localized primary pancreatic neuroendocrine neoplasms

Variable	Number of patients	Median DSS, months	P-value (univariate)	Median DFS, months	P-value (univariate)
Gender
Male	14	NR	97
Female	29	NR	0.457	NR	0.487
Age
<50 years	16	NR	NR
≥50 years	27	NR	0.896	97	0.400
Grade
Low	19	NR	NR
Intermediate	24	NR	0.244	97	0.091
Tumour size
<5 cm	29	NR	NR
≥5 cm	14	106	0.041	97	0.032
Tumour multifocality
Absent	37	NR	NR
Present	6	86	0.724	97	0.318
Margin
Negative	36	NR	NR
Positive	7	106	0.074	25	<0.001
Nodal status
Negative	25	NR	NR
Positive	18	NR	0.486	46	0.007
Vascular invasion
Absent	39	NR	NR
Present	4	NR	0.038	38	0.349
Perineural invasion
Absent	37	NR	NR
Present	6	NR	0.422	25	0.014

Statistically significant values are shown in bold

DFS, disease-free survival; DSS, disease-specific survival; NR, not reached