Table 4. Odds ratios and 95% confidence intervals for the association between CHRM1 haplotypes and myopia.

Haplotype*	rs11823728	rs544978	rs2186410	rs542269	Individuals with myopia > 6.0D (%)	Individuals with myopia < −0.5D (%)	p value**,#/ Cp-value##	Odds Ratio (95% CI***)
Ht1	G	G	A	A	272	138	0.086/0.258	1.36 (0.96–1.93)
Ht2	G	G	G	A	61	26	0.2/0.6	1.38 (0.84–2.25)
Ht3	G	A	A	G	38	25	0.52/1.56	0.84 (0.49–1.43)

The asterisk indicates the order of polymorphisms comprising CHRM1 haplotypes: rs11823728, rs544978, rs2186410, and rs542269. The haplotypes were identified by the Bayesian statistical method available in the program, Phase 2.1. The double asterisk means the χ² test (2×2 table) was performed to obtain the p value. The number of haplotypes in eyes with myopia greater than or equal to 6.0 D and less than or equal to 0.5 D with Ht1 was compared with the number of haplotypes in eyes with myopia greater than or equal to 6.0 D and less than or equal to 0.5 D without Ht1. A p value of less than 0.05 was considered statistically significant. Percentages may not add up to 100% because of the presence of rare haplotypes (below 0.3%) not presented in this table. ^#The χ² test or Fisher's exact test was performed to obtain the p-value. The percentages of people with and without HT1 were compared between myopia and control groups. It was considered statistically significant if p was less than 0.05. ^##Cp-value, p-value corrected by Bonferroni correction. The triple asterisk indicates CI=confidence interval.