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. Author manuscript; available in PMC: 2010 Jun 15.
Published in final edited form as: Bioorg Med Chem Lett. 2009 May 3;19(12):3229–3232. doi: 10.1016/j.bmcl.2009.04.100

Table 2.

IC50 values of compounds 6a, 6e and 6f, chloroquine and artemisinin against the W2, FCR3,3D7, VI/S and D6 P. falciparum strains.

Compd IC50/nM
W2 FCR3 3D7 VI/S D6
Chloroquine 78.1±6.91 51.1±0.1 11.6±1.1 65.0±4.1 16.9±2.1
Artemisinin 12.0±1.97 5.38±0.54 9.71±4.18 4.24±0.54 14.5±1.2
6a 4.09±0.13 1.75±0.32 3.11±0.72 1.59±0.11 4.71±0.12
6e 4.81±0.12 2.00±0.02 2.50±1.51 2.25±0.24 4.75±0.37
6f 4.21±0.56 1.89±0.10 2.48±0.41 1.65±0.11 4.96±0.66