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. Author manuscript; available in PMC: 2010 Aug 15.
Published in final edited form as: Biochem Pharmacol. 2009 Apr 24;78(4):344–354. doi: 10.1016/j.bcp.2009.04.016

Figure 3. Dicoumarol treatment sensitizes human G361 melanoma cells to DCPIP-induced apoptosis.

Figure 3

(A) Induction of cell death by exposure to DCPIP (40 µM, 24 h) in the absence or presence of the NQO1 inhibitor dicoumarol (DC, 60 µM) was assessed by flow cytometric analysis of annexinV-FITC/propidium iodide-stained cells. The numbers indicate viable cells (AV−, PI−, lower left quadrant) in percent of total gated cells (mean ± SD, n=3). (B) NQO1 protein levels in G361 and A375 cells were compared by immunoblot analysis.