Table 1.
Cross-sectional survey in the study population in October 2003: differences by hemoglobin genotype*
| AA αα/αα |
AA −α/αα |
AA −α/−α |
P † | AS αα/αα |
AS −α/αα −α/−α |
P ‡ | |
|---|---|---|---|---|---|---|---|
| No. | 36 | 66 | 26 | 6 | 14 | ||
| Age (months) |
52.6 (35.6–72.3) |
53.3 (39.7–77.3) |
68.4 (50.5–79.3) |
0.116 | 63.9 (56.2–67.8) |
65.6 (54.0–83.0) |
0.311 |
| WBCs (106/mL) |
7.4 (6.15–10.2) |
7.9 (6.2–9.7) |
7.7 (6.6–9.1) |
0.991 | 6.55 (5.7–7.9) |
7.6 (6–8.7) |
0.373 |
| RBCs (109/mL) |
4.3 (3.9–4.5) |
4.4 (4.1–4.6) |
5.0 (4.7–5.2) |
< 0.001 | 4.5 (3.9–4.8) |
4.7 (4.4–4.8) |
0.001 |
| Hb (mg/dL) |
11.3 (10.8–11.9) |
10.6 (10.2–11.5) |
10.4 (9.8–10.9) |
0.003 | 11.3 (10.1–12.7) |
10.7 (10.4–11.9) |
0.575 |
| WAZ | −0.8 (−2.3 to 0.2) |
−1.1 (−1.5 to −0.6) |
−1.2 (−2.2 to −0.4) |
0.158 | −1.6 (−3.2 to −0.6) |
−0.7 (−3.2 to 0.3) |
0.811 |
| HAZ | −0.9 (−2.3 to 0.36) |
−0.91 (−3.0 to −0.1) |
−1.2 (−2.4 to 0) |
0.388 | −1.8 (−4.9 to 0.3) |
−0.43 (−4.3 to 1.7) |
0.681 |
| CD14 (× 103/mL) |
105 (43–156) |
62 (27–99) |
69 (36–92) |
0.117 | 24§ (14–60) |
77 (53–128) |
0.472 |
| pDCs (× 103/mL) |
7.0 (3.0–10.2) |
5.0 (2.0–10.5) |
6.1 (2.2–10.7) |
0.169 | 10.1 (4.5–12.5) |
3.5 (2–5.5) |
0.142 |
| mDCs (× 103/mL) |
7.0 (3.1–10.6) |
4.0 (2.4–7.8) |
2.5 (1.0–6.5) |
0.043 | 2.6 (0.6–10.0) |
2.5§ (1.5–6.5) |
0.065 |
*
WBCs = white blood cells; RBCs = red blood cells; Hb = hemoglobin; WAZ = weight-for-age z score; HAZ = height-for-age z score; pDCs = plasma cytoid dendritic cells; mDCs = myeloid dendritic cells. Values in parentheses are 25th and 75th percentiles.
†
By Kruskal-Wallis H test for trend; degrees of freedom (df) = 2.
‡
By Kruskal-Wallis H test for trend; df = 2 comparing AA (αα/αα), AS (αα/αα), and AS (−α/αα or −α/−α).
§
P < 0.05 versus control, by Mann-Whitney U test.