Table 3.
Comparisons of children with severe malaria and during convalescence*
| AA αα/αα |
AA −α/αα |
AA −α/−α |
P † | |
|---|---|---|---|---|
| No. | 12 | 11 | 4 | |
| Age (months) | 19.5 (10.4–32.3) | 22.1 (12.6–40.9) | 20.2 (19.9–29) | 0.354 |
| WBCs (106/mL) | ||||
| Acute | 13.5 (8.2–20.0) | 10.9 (6.9–20.0) | 8.4 (8.1–11.2) | 0.796 |
| Convalescent | 11.7 (10.3–16.1) | 9.9 (6.3–13.0) | 8.0 (7.7–8.4) | 0.067 |
| RBC (109/mL) | ||||
| Acute | 2.8 (2.0–4.2) | 3.1 (1.9–3.8) | 4.1 (3.8–4.1) | 0.413 |
| Convalescent | 3.4 (3.2–4.3) | 3.5 (3.2–3.9) | 4.4 (4.2–4.4) | 0.128 |
| Hb (mg/dL) | ||||
| Acute | 7.3 (5.0–9.8) | 7.7 (4.5–8.7) | 7.5 (7.4–8.0) | 0.948 |
| Convalescent | 9.3 (8.5–10.9) | 9.1 (8.9–9.8) | 9.0 (8.8–9.6) | 0.972 |
| CD14 (× 103/mL) | ||||
| Acute | 416 (119–616) | 263 (207–628) | 814 (152–756) | 0.978 |
| Convalescent | 530 (323–943) | 9.93 (380–1,070) | 204 (161–264) | 0.158 |
| pDC (× 103/mL) | ||||
| Acute | 4.2 (2.3–10.0) | 6.7 (4.0–11.3) | 4.2 (2.6–20.4) | 0.608 |
| Convalescent | 10.4 (6.6–25) | 14.5 (5.9–22.0) | 2 (1.8–2.5) | 0.022 |
| mDC (× 103/mL) | ||||
| Acute | 9.5 (7.5–12.7) | 9.6 (3.1–23.1) | 6.4 (4.8–24.8) | 0.928 |
| Convalescent | 17.0 (9.5–32.0) | 15 (12.7–24) | 5 (4.3–6.4) | 0.045 |
*
WBCs = white blood cells; RBCs = red blood cells; Hb = hemoglobin; pDCs = plasma cytoid dendritic cells; mDCs = myeloid dendritic cells. Values in parentheses are 25th and 75th percentiles.
†
By Kruskal-Wallis H test for trend; degrees of freedom = 2.