Table 4.
Comparisons of children with acute malaria and during convalescence*
| AA αα/αα |
AA −α/αα |
AA −α/−α |
P † | |
|---|---|---|---|---|
| No. | 14 | 17 | 8 | |
| Age (months) | 28.5 (11.4–37.1) | 43.8 (16.0–53.2) | 37.8 (23.1–65.0) | 0.135 |
| WBCs (106/mL) | ||||
| Acute | 11.1 (7.6–19.0) | 8.6 (5.5–14.8) | 8.3 (7.1–13.5) | 0.625 |
| Convalescent | 11.5 (9.8–16.1) | 9.4 (6.2–12.0) | 7.7 (5.3–8.1) | 0.031 |
| RBCs (109/mL) | ||||
| Acute | 2.9 (2.2–4.2) | 3.5 (2.2–4.2) | 4.1 (3.8–4.7) | 0.075 |
| Convalescent | 3.5 (3.2–4.1) | 3.7 (3.3–4.4) | 4.4 (4.2–4.8) | 0.016 |
| Hb (mg/dL) | ||||
| Acute | 8.1 (5.4–9.7) | 8.6 (5.2–9.8) | 7.8 (7.4–9.4) | 0.833 |
| Convalescent | 9.5 (8.7–10.5) | 9 (8.7–10.0) | 8.9 (8.1–9.6) | 0.602 |
| CD14 (× 103/mL) | ||||
| Acute | 421 (192–542) | 468 (244–540) | 811 (274–1,321) | 0.335 |
| Convalescent | 720 (369–925) | 610 (390–933) | 258 (162–395) | 0.046 |
| pDCs (× 103/mL) | ||||
| Acute | 4.0 (3.0–7.1) | 6.8 (4.1–11.5) | 7.5 (3.2–12.5) | 0.375 |
| Convalescent | 10.3 (6.6–19.0) | 9.8 (5.9–19.5) | 4.2 (2.1–7.1) | 0.021 |
| mDCs (× 103/mL) | ||||
| Acute | 10.0 (7.5–16.4) | 10.3 (6.6–25.6) | 11.3 (5.1–31.9) | 0.954 |
| Convalescent | 21.1 (10.8–76.0)‡ | 13.3 (7.1–17.9) | 6.2 (3.5–11.5) | 0.010 |
*
For definitions of abbreviations, see Table 1. Values in parentheses are 25th and 75th percentiles.
†
By Kruskal-Wallis H test for trend, degrees of freedom = 2.
‡
Values due to extreme outliers; median (range) when these are excluded: 10.6 (7.0–13.9).