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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Drug Alcohol Depend. 2008 Dec 5;101(1-2):34–41. doi: 10.1016/j.drugalcdep.2008.10.016

Table 2. Rates of 33 Self-Reported Medication Side Effects in the Treatment Phase.

Side Effect 0 mg
(n = 16)
30 mg IR
(n = 12)
30 mg SR
(n = 10)

1. Change in appetite 50.0 66.7 80.0
2. Sleeping More 50.0 58.3 50.0
3. Sleeping Less 18.8 33.3 70.0*
4. More Anxious 18.8 33.3 50.0
5. Less Anxious 6.3 33.3 50.0*
6. More Unhappy 12.5 33.3 20.0
7. Happier 75.0 83.3 90.0
8. Coughing 62.5 66.7 70.0
9. Trouble Concentrating 31.3 25.0 40.0
10. Weight Changing 37.5 66.7 60.0
11. More Angry 25.0 25.0 50.0
12. Hands Shaking 0.0 0.0 20.0
13. Diarrhea 12.5 8.3 40.0
14. Constipation 18.8 8.3 30.0
15. Nausea 12.5 16.7 20.0
16. More Energy 50.0 58.3 60.0
17. Less Energy 18.8 8.3 30.0
18. Felt High 0.0 16.7 10.0
19. Chills 0.0 16.7 10.0
20. Fever 0.0 16.7 10.0
21. Heart Beating Slower 6.3 16.7 20.0
22. Heart Beating Faster 12.5 33.3 40.0
23. Breathe Faster 12.5 50.0 40.0
24. Dry Mouth 25.0 33.3 70.0
25. Runny Nose 31.3 25.0 40.0
26. Trouble with Eyes 37.5 33.3 60.0
27. Increased Urination 50.0 50.0 60.0
28. Drowsy 18.8 16.7 60.0
29. Muscles/Bones Ache 12.5 33.3 50.0
30. Felt Dizzy 6.3 8.3 30.0
31. Sleeping Better 43.8 66.7 70.0
32. Medication Too High 0.0 0.0 10.0
33. Medication Too Low 18.8 33.3 50.0

Note. A total of 42 subjects entered the 8-week treatment phase, but 4 subjects did not provide side effects ratings before being dropped from the study in weeks 1 (n = 2) and 2 (n = 2) of treatment for protocol violations. Accordingly side effect ratings are available for 38 subjects. The rates of ever experiencing a side effect in the 8-week treatment periods are presented, collapsing across time due to low weekly endorsement rates.

*

p<. 05.

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