Table 2. Rates of 33 Self-Reported Medication Side Effects in the Treatment Phase.
Side Effect | 0 mg (n = 16) |
30 mg IR (n = 12) |
30 mg SR (n = 10) |
|
---|---|---|---|---|
1. | Change in appetite | 50.0 | 66.7 | 80.0 |
2. | Sleeping More | 50.0 | 58.3 | 50.0 |
3. | Sleeping Less | 18.8 | 33.3 | 70.0* |
4. | More Anxious | 18.8 | 33.3 | 50.0 |
5. | Less Anxious | 6.3 | 33.3 | 50.0* |
6. | More Unhappy | 12.5 | 33.3 | 20.0 |
7. | Happier | 75.0 | 83.3 | 90.0 |
8. | Coughing | 62.5 | 66.7 | 70.0 |
9. | Trouble Concentrating | 31.3 | 25.0 | 40.0 |
10. | Weight Changing | 37.5 | 66.7 | 60.0 |
11. | More Angry | 25.0 | 25.0 | 50.0 |
12. | Hands Shaking | 0.0 | 0.0 | 20.0 |
13. | Diarrhea | 12.5 | 8.3 | 40.0 |
14. | Constipation | 18.8 | 8.3 | 30.0 |
15. | Nausea | 12.5 | 16.7 | 20.0 |
16. | More Energy | 50.0 | 58.3 | 60.0 |
17. | Less Energy | 18.8 | 8.3 | 30.0 |
18. | Felt High | 0.0 | 16.7 | 10.0 |
19. | Chills | 0.0 | 16.7 | 10.0 |
20. | Fever | 0.0 | 16.7 | 10.0 |
21. | Heart Beating Slower | 6.3 | 16.7 | 20.0 |
22. | Heart Beating Faster | 12.5 | 33.3 | 40.0 |
23. | Breathe Faster | 12.5 | 50.0 | 40.0 |
24. | Dry Mouth | 25.0 | 33.3 | 70.0 |
25. | Runny Nose | 31.3 | 25.0 | 40.0 |
26. | Trouble with Eyes | 37.5 | 33.3 | 60.0 |
27. | Increased Urination | 50.0 | 50.0 | 60.0 |
28. | Drowsy | 18.8 | 16.7 | 60.0 |
29. | Muscles/Bones Ache | 12.5 | 33.3 | 50.0 |
30. | Felt Dizzy | 6.3 | 8.3 | 30.0 |
31. | Sleeping Better | 43.8 | 66.7 | 70.0 |
32. | Medication Too High | 0.0 | 0.0 | 10.0 |
33. | Medication Too Low | 18.8 | 33.3 | 50.0 |
Note. A total of 42 subjects entered the 8-week treatment phase, but 4 subjects did not provide side effects ratings before being dropped from the study in weeks 1 (n = 2) and 2 (n = 2) of treatment for protocol violations. Accordingly side effect ratings are available for 38 subjects. The rates of ever experiencing a side effect in the 8-week treatment periods are presented, collapsing across time due to low weekly endorsement rates.
p<. 05.