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. 2009 Sep 21;4(9):e6988. doi: 10.1371/journal.pone.0006988

Figure 4. Categorical analysis of genes induced during iron starvation.

Figure 4

Pie charts represent the COG classification for the genes uniquely regulated in the conditions listed. Each pie represents 100% of the genes exhibiting significant gene expression changes following growth in iron depleted media. COG categories were identified for each differentially regulated gene based on genomic annotation (GenBank accession, NC_007530). To simplify the analysis, the COG categories were grouped into general categories as follows: Categories A, J, K, L, and RNA genes were merged into “Transcription/translation/DNA replication/RNA”; C, E, F, G, H, I, P, and Q were combined into “Transport and metabolism”; COGs N, T, and U were combined into “Cellular functions/trafficking/secretion/signal transduction”; and categories R and S were grouped with uncategorized genes and classified as “Unknown.” Other COG categories listed are reported as they were originally defined.