TABLE 1.
PATIENT CHARACTERISTICS
| PCV7 (n = 57) | PPSV23 (n = 63) | P Value | ||||
|---|---|---|---|---|---|---|
| Age, years | 63 ± 10 | 63 ± 10 | 0.95 | |||
| Male, % | 38 (67) | 37 (59) | 0.45 | |||
| White, % | 43 (75) | 48 (76) | 1.0 | |||
| FEV1, L | 1.40 ± 0.58 | 1.23 ± 0.54 | 0.12 | |||
| FEV1, % predicted | 45 ± 16 | 43 ± 15 | 0.56 | |||
| FEV1/FVC | 0.47± 0.13 | 0.44 ± 0.13 | 0.16 | |||
| Oxygen use, % | 12 (21) | 21 (33) | 0.15 | |||
| Inhaled corticosteroid use, % | 36 (63) | 43 (68) | 0.57 | |||
| Pack-years smoking | 54 ± 32 | 55 ± 34 | 0.82 | |||
| Comorbid illness, % | ||||||
| Coronary artery disease | 16 (28) | 15 (24) | 0.68 | |||
| Congestive heart failure | 3 (5) | 2 (3) | 0.67 | |||
| Stroke | 2 (4) | 6 (9) | 0.28 | |||
| Diabetes mellitus | 5 (9) | 3 (5) | 0.48 | |||
| Prior malignancy | 7 (12) | 8 (13) | 1.00 | |||
| Anemia | 7 (12) | 4 (6) | 0.35 | |||
| Previous pneumonia, % | 26 (46) | 30 (48) | 0.86 | |||
| Exacerbation history (yr before enrollment) | ||||||
| Hospitalized or unscheduled emergency visit, % | 10 (18) | 9 (14) | 0.80 | |||
| Received systemic steroids and/or antibiotics, % | 26 (46) | 26 (41) | 0.71 | |||
| Vaccine naive, % | 30 (53) | 33 (52) | 1.00 | |||
| Years since last vaccination | 7.9 | 8.4 | 0.56 | |||
Definition of abbreviations: PCV7 = 7-valent diphtheria-conjugated pneumococcal polysaccharide vaccine; PPSV23 = 23-valent pneumococcal polysaccharide vaccine.