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. 2009 Jun 25;180(6):499–505. doi: 10.1164/rccm.200903-0488OC

TABLE 3.

BASELINE AND 1-MONTH SEROTYPE-SPECIFIC GEOMETRIC MEAN IgG ANTIBODY LEVELS

Baseline IgG μg/ml (95% CI)
1-Month IgG μg/ml (95% CI)
Serotype PCV7 PPSV23 PCV7 PPSV23
4 0.26 (0.17–0.38) 0.32 (0.23–0.44) 2.03 (1.24–3.32) 0.70 (0.47–1.03)
6B 0.90 (0.65–1.25) 0.85 (0.67–1.08) 2.96 (1.96–4.48) 1.76 (1.23–2.52)
9V 0.86 (0.61–1.20) 0.76 (0.55–1.06) 4.69 (3.27–6.74) 2.09 (1.47–2.97)
14 2.88 (1.86–4.46) 2.90 (1.96–4.27) 17.2 (11.7–25.3) 11.22 (7.42–16.96)
18C 1.26 (0.84–1.89) 1.17 (0.83–1.64) 9.26 (6.29–13.6) 3.70 (2.58–5.29)
19F 3.20 (2.43–4.21) 3.16 (2.55–3.93) 7.33 (5.16–10.4) 6.20 (4.75–8.09)
23F 0.75 (0.52–1.07) 0.55 (0.40– 0.76) 7.31 (4.56–11.7) 1.52 (0.99–2.32)

Definition of abbreviations: OPK = opsonophagocytosis killing index; PCV7 = 7-valent diphtheria-conjugated pneumococcal polysaccharide vaccine; PPSV23 = 23-valent pneumococcal polysaccharide vaccine.

Within each study group, postvaccination antibody levels and OPK were higher than baseline (P < 0.01) for all serotypes. Bolded items represent a significant difference in absolute postvaccination IgG levels between vaccine groups and underlined items represent a significant difference in 1 month to baseline IgG ratio.