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. 2009 Oct 20;4(10):e7165. doi: 10.1371/journal.pone.0007165

Figure 2. Overall structure of the kinase domain of GNE.

Figure 2

The C-terminal helix (residues 700–717, in green) is embedded into the N-lobe subdomain. The ROK family signature zinc-binding motif (cyan) is located on top of two parallel helices of the C-lobe. Residues 475–498 in the N-lobe are missing in the electron density map and are presented by dotted line (black).