Table 2. Distribution of relatively common HLA-A, -B, -C, and -DRB1 variants in similar case-control populations studied here (this study, N = 298) and elsewhere (N = 312).

HLA-A allele frequency			HLA-B allele frequency			HLA-C allele frequency			HLA-DRB1 allele frequency
Alleles	Elsewhere	This study	Alleles	Elsewhere	This study	Alleles	Elsewhere	This study	Alleles	Elsewhere	This study
A*01	0.172	0.171	B*07	0.130	0.128	Cw*01	0.032	0.022	*01	0.104	0.106
A*02	0.289	0.310	B*08	0.096	0.111	Cw*02	0.045	0.052	*03	0.131	0.114
A*03	0.111	0.141	B*13	0.019	0.032	Cw*03	0.131	0.153	*04	0.149	0.161
A*11	0.069	0.057	B*14	0.042	0.018	Cw*04	0.112	0.111	*07	0.117	0.134
A*23	0.034	0.020	B*15	0.074	0.081	Cw*05	0.080	0.086	*08	0.035	0.040
A*24	0.083	0.079	B*18	0.055	0.052	Cw*06	0.088	0.109	*09	0.010	0.008
A*25	0.022	0.025	B*27	0.037	0.042	Cw*07	0.293	0.310	*10	0.013	0.012
A*26	0.034	0.022	B*35	0.093	0.087	Cw*08	0.050	0.017	*11	0.103	0.092
A*29	0.039	0.025	B*37	0.018	0.027	Cw*12	0.066	0.070	*12	0.018	0.018
A*30	0.030	0.022	B*38	0.018	0.013	Cw*14	0.016	0.008	*13	0.141	0.121
A*31	0.018	0.017	B*40	0.067	0.082	Cw*15	0.040	0.022	*14	0.026	0.027
A*32	0.026	0.050	B*44	0.130	0.153	Cw*16	0.034	0.030	*15	0.135	0.149
A*33	0.018	0.005	B*49	0.021	0.008	Cw*17	0.011	0.010	*16	0.019	0.017
A*68	0.050	0.045	B*51	0.058	0.042	Others	0.002	0
Others	0.008	0.011	B*52	0.016	0.020
			B*55	0.037	0.010
			B*57	0.027	0.042
			Others	0.064	0.049

Previously studied population consists of European Americans from the San Francisco Bay area [16]. Rare alleles at each locus are grouped together (others), with number of chromosomes (2N) used as the denominator in all tabulations. Between study populations, statistically significant differences (p≤0.025) are seen with A*32, B*14, B*55, and Cw*08.