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. Author manuscript; available in PMC: 2009 Sep 14.
Published in final edited form as: Biochemistry. 2005 Dec 20;44(50):16574–16583. doi: 10.1021/bi0518186

Scheme 1. Role of the deacetylase LpxC in the biosynthesis of lipid A.

Scheme 1

LpxA and LpxC are cytoplasmic enzymes. The enzymology and genetics of the lipid A pathway are best characterized in E. coli (15).