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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Radiat Res. 2009 Jun;171(6):698–707. doi: 10.1667/RR1685.1

FIG. 1.

FIG. 1

The effect of SOM230 on overall survival and median survival time with administration starting 2 h before and continuing for 2 weeks after TBI. Panel A : Kaplan-Meier survival curve from mice exposed to 9 Gy TBI. SOM230 significantly reduced lethality and prolonged survival (0.5 mg/kg b.i.d. P = 0.006; 2 mg/kg b.i.d. P = 0.0003; 5 mg/kg b.i.d. P = 0.0001). Panel B: Survival time (median and interquartile range) in mice exposed to 9 Gy TBI. SOM230 prolonged the median survival time after TBI (P < 0.05 at all doses). The animals were observed up to 30 days after TBI, n = 8.