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The effect of co-administration of SOM230 and pancreatic enzymes on overall survival after TBI. Kaplan-Meier survival curve from mice exposed to 9 Gy TBI. The beneficial effect of SOM230 on survival after TBI was reversed by co-administration of pancreatic enzymes (P = 0.009). V: vehicle; PE: pancreatic enzymes. SOM230: 5 mg/kg b.i.d.; pancreatic enzymes: 200 mg/kg b.i.d; n = 8.
