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Effect of TBI and SOM230 on circulating levels of IL-12 and CXCL9. Panel A: SOM230-treated animals showed significantly lower circulating IL-12 levels than vehicle-treated animals (P = 0.007). Panel B: CXCL9 plasma levels gradually decreased after 8 Gy TBI (P = 0.003). No difference between vehicle- and SOM230-treated animals was observed. SOM230: 0.5 mg/kg b.i.d.; n = 6.
