Table 2.
Factors associated with JC virus (JCV) infection among controls, Washington County, MD, 1975 to 2006
| JCV-positive |
JCV-negative |
||||
|---|---|---|---|---|---|
| Characteristic | n | % | n | % | p-value |
| Sex | |||||
| male | 266 | 70.0 | 114 | 30.0 | |
| female | 341 | 72.2 | 131 | 27.8 | 0.48 |
| Age (years) | |||||
| < 35 | 30 | 83.3 | 6 | 16.7 | |
| 35–44 | 67 | 72.8 | 25 | 27.2 | |
| 45–54 | 173 | 70.9 | 71 | 29.1 | |
| 55–64 | 172 | 67.5 | 83 | 32.5 | |
| 65–74 | 123 | 73.2 | 45 | 26.8 | |
| 75+ | 34 | 69.4 | 15 | 30.6 | 0.09 |
| Smoking status | |||||
| current | 125 | 74.0 | 44 | 26.0 | 0.871 |
| former | 156 | 65.5 | 82 | 34.5 | 0.031 |
| never | 326 | 73.3 | 119 | 26.7 | |
| Body mass index (kg/m2)2 | |||||
| < 25 | 91 | 58.7 | 64 | 41.3 | |
| 25–30 | 81 | 49.4 | 83 | 50.6 | |
| 30+ | 25 | 41.0 | 36 | 59.0 | 0.05 |
| NSAID use at baseline (past 48 hours)3 | |||||
| yes | 174 | 28.7 | 64 | 26.1 | |
| no | 433 | 74.3 | 181 | 73.9 | 0.45 |
| Family history of colorectal cancer2 | |||||
| no | 127 | 51.2 | 121 | 48.8 | |
| yes | 22 | 52.4 | 20 | 47.6 | 1.00 |
| Recent hormone use2 | |||||
| none | 83 | 50.0 | 83 | 50.0 | |
| any | 19 | 54.3 | 16 | 45.7 | 0.71 |
p-values correspond to comparison between current versus never smokers and former versus never smokers
data obtained from CLUE II participants only
NSAID use within 48 hours prior to blood draw