Table 1.
Cytotoxicity Data
| IC50 (μM) ± SEMa | ||
|---|---|---|
| Compound | HL-60 | NCI-H460 |
| 1 | 3.95 ± 0.24 | 0.35 ± 0.017 |
| 4a | 2.97 ± 0.11 | 0.028 ± 0.0024 |
| 4b | 0.47 ± 0.06 | 0.026 ± 0.0022 |
Concentrations of compound that reduce cell viability by 50%, determined by cell proliferation assays. Cells were incubated with platinum for 72 h. Values are means of four experiments ± the standard error of the mean.