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. Author manuscript; available in PMC: 2009 Dec 11.
Published in final edited form as: J Med Chem. 2008 Dec 11;51(23):7574–7580. doi: 10.1021/jm800900g

Table 1.

Cytotoxicity Data

IC50 (μM) ± SEMa
Compound HL-60 NCI-H460
1 3.95 ± 0.24 0.35 ± 0.017
4a 2.97 ± 0.11 0.028 ± 0.0024
4b 0.47 ± 0.06 0.026 ± 0.0022
a

Concentrations of compound that reduce cell viability by 50%, determined by cell proliferation assays. Cells were incubated with platinum for 72 h. Values are means of four experiments ± the standard error of the mean.