Table 1.
Demographic and haemodynamic characteristics.
| Parameters | Healthy volunteers | Patients |
|---|---|---|
| Demographics | ||
| No of subjects | n=17 | n=101 |
| Age (yrs) | 61±6 | 63±11 |
| Male sex | 12/17 (71%) | 75/101 (74%) |
| Coronary risk factors | ||
| Arterial hypertension | 0/17 (0%) | 89/101 (88%) |
| Hypercholesterolemia | 0/17 (0%) | 66/101 (65%) |
| Diabetes mellitus | 0/17 (0%) | 22/101 (22%) |
| Family history | 0/17 (0%) | 30/101 (30%) |
| Smoker | 0/17 (0%) | 25/101 (25%) |
| Prior percutaneous coronary intervention | 0/17 (0%) | 35/101 (35%) |
| Prior myocardial infarction | 0/17 (0%) | 25/101 (25%) |
| Prior coronary artery bypass grafting | 0/17 (0%) | 5/101 (5%) |
| Reasons for referral | ||
| Chest pain | (n/a) | 83 (82%) |
| Exertional dyspnoea | (n/a) | 18 (18%) |
| Baseline haemodynamics | ||
| Mean blood pressure (mmHg) | 92±6 | 89±12 |
| Heart rate (1/min) | 67±10 | 66±18 |
| Double product (mmHg/min) | 8339±1233 | 8298±2604 |
| Peak stress haemodynamics | ||
| Mean blood pressure (mmHg) | 92±12 | 109±22 |
| Heart rate (1/min) | 149±6 | 138±11 |
| Double product (mmHg/min) | 19514±2275 | 20029±4327 |
| Baseline MR-parameters | ||
| LV end-diastolic diameter (mm) | 49±4 | 52±5 |
| LV end-systolic diameter (mm) | 32±4 | 35±6 |
| LV end-diastolic volume (ml) | 144±29 | 147±39 |
| LV end- systolic volume (ml) | 47±14 | 58±28 |
| Baseline ejection fraction (%) | 67±6 | 61±10 |
| No of segments with resting wall motion abnormalities by cine | 0/272 (0%) | 72/1616 (4%) |
Data presented as number of patients or as mean±standard deviation; n/a indicates not applicable.