Table 3.
Analysis of XNC10 putative antigen binding residues
| Docking | X. laevis Class Ia | XNC1-9 | XNC10 |
|---|---|---|---|
| Peptide N-terminus | |||
| Tyr7 | Tyr | 6 Tyr, 2 Phe | Tyr |
| Tyr59 | Tyr | 1 Tyr, 8 His | Asp/Asn* |
| Tyr159 | Tyr | 4 Tyr, 4 Phe | Tyr |
| Trp167 | Trp/Gly | 2 Gln, 6 His | Gln |
| Tyr171 | Tyr | 7 Tyr | His* |
| Peptide C-terminus | |||
| Tyr84 or Arg84 | Arg | 3 Tyr, 1 Arg, 3 Phe, 2 Val | Ser* |
| Thr143 | Thr | 4 Val, 3 Met, 1 Leu | Ala* |
| Lys146 | Lys | 3 Gln, 5 Leu | Lys* |
| Trp147 | Trp | 7 Trp, 1 Leu | Arg* |
Numbering based on HLA-A2; Table modified from Flajnik et al 1993
*
= XNC10-specific residues