Figure 4.

Increase in spike duration over the course of the burst. A, Multiple sweeps of all spikes in a single burst, aligned at the peak. B, Averaged traces of the first and last spike from 100 bursts. C, Spike duration at 1/6 of the amplitude of the first spike from 100 bursts in a single experiment. Single data points are superimposed with mean values sorted by spike index (±SD in x and y). D, Across experiments, the change in spike duration was not dependent on the maximum instantaneous spike frequency. E, Across experiments, the change in spike duration was dependent on the interburst membrane potential (Vm). F, Across experiments, the baseline depolarization under the burst maximum trough amplitude) was dependent on the increase in spike duration. adj., Adjusted.