. Author manuscript; available in PMC: 2010 Aug 1.

Published in final edited form as: Neurosci Res. 2009 May 3;64(4):413–420. doi: 10.1016/j.neures.2009.04.015

Table 4.

Functional annotation clustering of the selected lithium-responsive genes.

Functional cluster 1
Category	Term	p-value^a	Fold Enrichment^b
SP PIR keywords	aminotransferase	0.0016	49.3
GO:0008483	transaminase activity	5.79E−03	25.7
GO:0016769	transferase activity, transferring nitrogenous groups	7.29E−03	22.8

Functional cluster 2
GO:0006520	amino acid metabolic process	8.05E−04	6.11
GO:0006519	amino acid and derivative metabolic process	0.0020	5.10
GO:0009308	amine metabolic process	0.0145	3.39
GO:0006807	nitrogen compound metabolic process	0.0165	3.30

Functional cluster 3
GO:0008652	amino acid biosynthetic process	0.0030	13.4
GO:0009309	amine biosynthetic process	0.0070	9.96
GO:0044271	nitrogen compound biosynthetic process	0.0075	9.69

Modified Fisher Exact p-value (EASE score),

Enrichment factor for the lithium-responsive genes (fold change >1.2; FDR<0.05) in each category.