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. Author manuscript; available in PMC: 2009 Sep 14.
Published in final edited form as: Eur J Immunol. 2008 Aug;38(8):2168–2179. doi: 10.1002/eji.200838155

Figure 7.

Figure 7

Effect of CxCR3 neutralization on RSV-induced pathophysiology. (A) Airway hyperreactivity (AHR) was assessed in uninfected, Ig-treated/RSV-infected (Ctrl RSV) and antiCxCL10-treated/RSV-infected (aCxCL10) mice by plethysmography on day 8 post-infection. Change in resistance represents the increase over baseline in response to methacholine challenge. Bars represent the mean of 10 mice per group ± SEM . (B) The expression of the mucus-associated genes Muc5ac and Gob5 was determined by real-time PCR of whole lung RNA (day 8 post-infection). Bars represent the mean of 5 mice per group from one of two independent experiments. *p < 0.05 vs. uninfected, #p<0.05 vs. control Ig-treated/RSV infected.