Table 1.
Participant Characteristics at Baseline [M ± (SD) or Percentage]
| Naltrexone* (n = 88) |
Placebo (n = 85) |
|
|---|---|---|
| Age | 29.9 ± 12.0 | 28.1 ± 10.7 |
| Gender (% male) | 58 | 60 |
| Alcohol dependent (%) | 65 | 60 |
| Caucasian (%) | 90 | 95 |
| Years of education | 14.9 (1.7) | 14.8 (1.6) |
| Family history positive for alcoholism (%) | 39 | 39 |
| Smoker (%) | 33 | 37 |
| DRD4: % with ≥ 7 repeats (n = 115) | 37 | 39 |
| OPRM1: % with aspartate (n = 107) | 33 | 29 |
| Drinks per day | 4.9 (2.6) | 4.5 (1.8) |
| Drinks per drinking day | 7.6 (3.8) | 6.9 (2.6) |
| Drinking days (%) | 65.0 (17.0) | 65.6 (16.0) |
| Heavy drinking days (%) | 45.8 (18.3) | 43.6 (18.8) |
| CES-D sum | 10.6 (8.9) | 10.4 (6.6) |
| FTND score in smokers (n = 61) | 2.5 (2.3) | 1.7 (2.6) |
| DRINC score | 23.6 (17.8) | 21.2 (14.9) |
*
There are no significant differences between the groups on these measures.